Santa Fe, New Mexico – March 7, 2025 – Hollywood legend Gene Hackman, known for iconic roles in The French Connection and Unforgiven, passed away at 95 due to heart disease worsened by Alzheimer’s, authorities confirmed Friday. His wife, Betsy Arakawa, 65, died days earlier from a rare hantavirus infection, ending the couple’s 30-year marriage in a heartbreaking sequence of events.

Gene Hackman’s Final Days in Santa Fe

Gene Hackman’s cause of death was linked to long-standing heart issues and advanced Alzheimer’s, according to New Mexico’s chief medical investigator, Dr. Heather Jarrell. The actor, who retired in 2004, was found in his Santa Fe home on February 26 during a welfare check. His pacemaker indicated he likely died around February 18. “His heart disease was severe, and Alzheimer’s left him unaware of his surroundings,” Jarrell explained.

Betsy Arakawa, a talented pianist, succumbed to hantavirus pulmonary syndrome (HPS) on February 11. Surveillance footage showed her last outing at a local pharmacy before returning home. HPS, spread through contact with infected rodent droppings, has a high mortality rate (38%-50%) and marked New Mexico’s first 2025 case.

How Did Gene Hackman Die? Heart Disease and Alzheimer’s Explained

Hackman’s autopsy revealed “hypertensive and atherosclerotic cardiovascular disease” – a form of heart disease caused by high blood pressure and artery plaque buildup. Combined with Alzheimer’s, his health rapidly declined. Dr. Jarrell noted his empty stomach suggested he hadn’t eaten recently, though dehydration wasn’t a factor.

The actor’s medical history included a 1990 angioplasty for heart failure. In his final years, Alzheimer’s likely left him confused, possibly unaware of his wife’s death.

Betsy Arakawa’s Tragic Death from Hantavirus

Arakawa’s passing shocked many due to hantavirus’s rarity. The virus, carried by deer mice, spreads when people inhale dust contaminated by rodent urine or droppings. Symptoms mimic the flu but escalate to severe breathing issues. Dr. Erin Phipps, New Mexico’s public health veterinarian, confirmed traces of rodents in the couple’s outbuildings, though the home itself was low-risk.

Investigators Rule Out Foul Play

Authorities initially found the deaths “suspicious” due to the couple’s decomposed state and a deceased dog. However, Sheriff Adan Mendoza confirmed no foul play. “No signs of break-ins or trauma were found,” he said. The dog’s death, possibly from starvation, remains under review.

Remembering Gene Hackman’s Legacy

Hackman’s family mourned his loss in a statement: “To the world, he was a star. To us, he was Dad and Grandpa.” Tributes poured in from co-stars like Clint Eastwood, who called him “a once-in-a-generation talent.”

FAQs About Gene Hackman’s Death

What was Gene Hackman’s cause of death?

Heart disease worsened by Alzheimer’s.

How did Betsy Arakawa die?

Hantavirus pulmonary syndrome from infected rodent exposure.

Where did Gene Hackman die?

His Santa Fe, New Mexico home.

Was there foul play?

No. Both deaths were natural.

What’s hantavirus’ mortality rate?

Between 38% and 50% in the Southwest.

Did Gene Hackman know his wife died?

Unlikely, due to his Alzheimer’s.

A Poignant End for a Hollywood Icon

The couple’s deaths highlight life’s unpredictability, even for a celebrated actor. As investigations close, fans worldwide remember Hackman’s brilliance on screen and the quiet strength of his wife beside him.